Western blot analysis of extracts from 293 cells, using TIMP1 antibody.
Western blot analysis of extracts from 293 cells, using TIMP1 antibody.
TIMP1 Antibody
CSB-PA152790
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetTIMP1
Overview
- SupplierCusabio
- Product NameTIMP1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7076
- Target nameTIMP1
- Target descriptionTIMP metallopeptidase inhibitor 1
- Target synonymsCLGI; collagenase inhibitor; EPA; epididymis secretory sperm binding protein; EPO; erythroid potentiating activity; fibroblast collagenase inhibitor; HCI; metalloproteinase inhibitor 1; TIMP; TIMP-1; tissue inhibitor of metalloproteinases 1
- HostRabbit
- IsotypeIgG
- Protein IDP01033
- Protein NameMetalloproteinase inhibitor 1
- Scientific DescriptionMetalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Anieta M. Sieuwerts, Clin. Chem., May 2007; 10.1373. KM Fong, Clin. Cancer Res., Aug 1996; 2: 1369. E. Susol, Rheumatology, Dec 2000; 39: 1332 - 1336. Christopher J Jackson, Ann Rheum Dis, Mar 1998; 57: 158 - 161.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203