TIMP2 (Tissue Inhibitor of Metalloproteinase 2) (3A4), CF640R conjugate, 0.1mg/mL [26628-22-8]

Biotium

TIMP2 (Tissue Inhibitor of Metalloproteinase 2) (3A4), CF640R conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

3A4

0.1 mg/ml

Other Conjugate

TIMP2

TIMP metallopeptidase inhibitor 2

CSC-21K; DDC8; metalloproteinase inhibitor 2; testicular secretory protein Li 57; tissue inhibitor of metalloproteinases 2

Mouse

IgG2a

Metalloproteinase inhibitor 2

This antibody recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Guinea Pig, Human, Mouse, Rabbit, Rat, Zebra Fish

2°C to 8°C

12352203