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TIMP3(Rabbit PAb), CF405S conjugate, 0.1mg/mL [26628-22-8]

TIMP3(Rabbit PAb), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC040408
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Equine, Human, Mouse, Rabbit, Rat
TargetTIMP3
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Overview

  • Supplier
    Biotium
  • Product Name
    TIMP3(Rabbit PAb), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Clone ID
    PAb
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID7078
  • Target name
    TIMP3
  • Target description
    TIMP metallopeptidase inhibitor 3
  • Target synonyms
    HSMRK222; K222; K222TA2; metalloproteinase inhibitor 3; MIG-5 protein; protein MIG-5; SFD; TIMP-3; tissue inhibitor of metalloproteinases 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP35625
  • Protein Name
    Metalloproteinase inhibitor 3
  • Scientific Description
    TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Canine, Equine, Human, Mouse, Rabbit, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203