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Tinostamustine (hydrochloride)

HY-101780A
MedChem Express
CAS Number1793059-58-1
Product group Chemicals
Molecular Weight451.82
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tinostamustine (hydrochloride)
  • Delivery Days Customer
    9
  • CAS Number
    1793059-58-1
  • Certification
    Research Use Only
  • Molecular Formula
    C19H29Cl3N4O2
  • Molecular Weight
    451.82
  • Scientific Description
    Tinostamustine hydrochloride (EDO-S101 hydrochloride) is a compound with anti-multiple myeloma activity and the ability to promote CD38 expression. Tinostamustine hydrochloride enhances the sensitivity of tumor cells to the anti-CD38 monoclonal antibody daratumumab by increasing the acetylation level of histone H3. Tinostamustine hydrochloride can increase the expression of MICA and MICB, thereby activating NK cells. Tinostamustine hydrochloride can significantly delay tumor growth and improve the survival rate of mice [1] .
  • SMILES
    O=C(NO)CCCCCCC1=NC2=CC(N(CCCl)CCCl)=CC=C2N1C.Cl
  • UNSPSC
    12352200