Tivozanib (hydrochloride hydrate)

MedChem Express

Tivozanib (hydrochloride hydrate)

10

Research Use Only

99.77

C22H22Cl2N4O6

509.34

Tivozanib hydrochloride hydrate is the hydrate hydrochloride form of Tivozanib (HY-10977). Tivozanib hydrochloride hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor ( VEGFR )-1, 2 3, with IC 50 s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrochloride hydrate exhibits antitumor efficacy [1] .

O=C(NC1=CC=C(C=C1Cl)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC4=NOC(C)=C4.Cl.O

2°C to 8°C

12352200