Tivozanib(AV-951)
ORB154729
CAS Number475108-18-0
Product group Chemicals
Molecular Weight454.86306
Overview
- SupplierBiorbyt
- Product NameTivozanib(AV-951) [475108-18-0]
- Delivery Days Customer16
- CAS Number475108-18-0
- CertificationResearch Use Only
- Molecular FormulaC22H19ClN4O5
- Molecular Weight454.86306
- Scientific DescriptionTivozanib (AV-951, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 0.21 nM/0.16 nM/0.24 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met EGFR and IGF-1R.
- SMILESO=C(NC1=CC=C(C=C1Cl)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC4=NOC(C)=C4
- UNSPSC12352200