Tivumecirnon

MedChem Express

Tivumecirnon

5

Research Use Only

99.85

C24H27Cl2F3N6O

543.41

Tivumecirnon (FLX475) is an orally active, selective CCR4 antagonist. Tivumecirnon blocks the binding of CCR4 to its ligands, CCL17 and CCL22 , thereby reducing Treg infiltration into the tumor microenvironment. Tivumecirnon has antitumor activity [1] [2] [3] [4] .

C[C@H](C1=C(C=C(C=C1)Cl)Cl)N2C3=NC(N4CC([C@H]5CCCN(C5)CCO)C4)=CN=C3C(C(F)(F)F)=N2

-20°C,2°C to 8°C

12352200