TK-129
T60713
Overview
- SupplierTargetMol Chemicals
- Product NameTK-129
- Delivery Days Customer10
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameTK-129
- Molecular FormulaC15H23N5O2
- Molecular Weight305.38
- Scientific DescriptionTK-129 is an orally active, potent inhibitor of KDM5B with an IC50 of 44 nM and is low-toxicity. TK-129 exhibits cardioprotective effects by inhibiting KDM5B and blocking the KDM5B-associated Wnt pathway. TK-129 can be used in cardiovascular disease studies to reduce isoprenaline-induced myocardial remodelling and fibrosis in vivo, as well as to reduce ang II-induced activation of cardiac fibroblasts in vitro [1].
- Shelf life instruction3 years
- Storage Instruction-20°C
- UNSPSC12352200