TLE6 Polyclonal Antibody
RD252751A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTLE6
Overview
- SupplierReddot Biotech
- Product NameTLE6 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.38 mg/ml
- ConjugateUnconjugated
- Gene ID79816
- Target nameTLE6
- Target descriptionTLE family member 6, subcortical maternal complex member
- Target synonymsGRG6; PREMBL; transducin like enhancer of split 6; transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila); transducin-like enhancer protein 6
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203