Western blot analysis of extracts from rat brain cells and NIH/3T3 cells, using TLK1 antibody.
Western blot analysis of extracts from rat brain cells and NIH/3T3 cells, using TLK1 antibody.
TLK1 Antibody
CSB-PA178566
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetTLK1
Overview
- SupplierCusabio
- Product NameTLK1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9874
- Target nameTLK1
- Target descriptiontousled like kinase 1
- Target synonymsPKU-beta; serine threonine protein kinase; serine/threonine-protein kinase tousled-like 1; SNARE protein kinase SNAK
- HostRabbit
- IsotypeIgG
- Protein IDQ9UKI8
- Protein NameSerine/threonine-protein kinase tousled-like 1
- Scientific DescriptionRapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at Ser-10. Yamakawa A., Gene 202:193-201(1997). Sillje H.H.W., EMBO J. 18:5691-5702(1999). Cabaniols J.-P., Mol. Biol. Cell 10:4033-4041(1999).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203