Fig-1:Induction of TLR3 activity by poly(I:C) in TLR3/NF-kB HEK293 cells.
Fig-1:Induction of TLR3 activity by poly(I:C) in TLR3/NF-kB HEK293 cells.
TLR3/NF-kB Luciferase Reporter-HEK293 Cell Line
RC1028
Category(Cell) Culture
Product group (Cell) Culture
Overview
- SupplierBoster Bio
- Product NameTLR3/NF-kB Luciferase Reporter-HEK293 Cell Line
- Delivery Days Customer9
- ApplicationsFunctional Assay
- CertificationResearch Use Only
- Scientific DescriptionThe TLR3/NF-kB Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses full-length human Toll-like receptor 3 (TLR3) and Renilla luciferase reporter gene under the transcriptional control of the NF-kB response element. Functional activity of the cell line has been validated by TLR3 ligand assay, in which upon activation by poly (I:C), TLR3 quickly initiates TRIF-dependent signaling pathway and mediates nuclear translocation of NF-kB (Figure 1).
- Storage InstructionLiquid Nitrogen
- UNSPSC12352207