Fig-1: Induction of TLR4 activity by LPS in TLR4/IL-8 HeLa cells.
Fig-1: Induction of TLR4 activity by LPS in TLR4/IL-8 HeLa cells.
TLR4/IL-8 Luciferase Reporter-HeLa Cell Line
RC1024
Product group (Cell) Culture
Overview
- SupplierBoster Bio
- Product NameTLR4/IL-8 Luciferase Reporter-HeLa Cell Line
- Delivery Days Customer9
- ApplicationsFunctional Assay
- CertificationResearch Use Only
- Scientific DescriptionThe TLR4/IL-8 Luciferase Reporter cell line is a stably transfected HeLa cell line which expresses human TLR4, MD-2 and CD14 as well Renilla luciferase reporter gene under the transcriptional control of the IL-8 promoter. IL-8 is one of the major pro-inflammatory cytokines induced by ligand (such as LPS)-mediated Toll-like receptor 4 (TLR4) activation. TLR4 is one of the key innate immune receptors, which is activated by LPS and can lead to sepsis upon dysregulation. The TLR4/IL-8 activation by LPS is shown in Figure 1.
- Storage InstructionLiquid Nitrogen
- UNSPSC12352207