TLR5 antibody

GeneTex

TLR5 antibody

9

WB: 0.5 - 2 microg/mL. IHC-P: 10 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

TLR5

toll like receptor 5

MELIOS; SLE1; SLEB1; systemic lupus erythematosus susceptibility 1; TIL3; toll/interleukin-1 receptor-like protein 3; toll-like receptor 5

Rabbit

IgG

Toll-like receptor 5

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203