TLR7/8 agonist 8
HY-153543
Overview
- SupplierMedChem Express
- Product NameTLR7/8 agonist 8
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC24H30N6O
- Molecular Weight418.53
- Scientific DescriptionTLR7/8 agonist 8 (compound 24m) is a potent toll-like receptor 7/8 (TLR7/8) dual agonist, with EC50s of 27 and 12 nM for hTLR7 and hTLR8, respectively. TLR7/8 agonist 8 can improve the antitumor activity of PD-1/PD-L1 blockade[1].
- SMILESCCCCNC1=C2N=C(CC3=CC=C(CN4CC5(C4)COC5)C=C3)C=CC2=NC(N)=N1
- UNSPSC12352200