TLR7/8/9 antagonist 2
HY-153460
Molecular Weight405.54
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameTLR7/8/9 antagonist 2
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC23H31N7
- Molecular Weight405.54
- Scientific DescriptionTLR7/8/9 antagonist 2 is an orally active TLR7/8/9 antagonist. TLR7/8/9 antagonist 2 has inhibitory activities for HEK/hTLR7, HEK/hTLR8 and HEK/hTLR9 with IC50 values of 0.011 microM, 0.029 microM and 0,052 microM, respectively.TLR7/8/9 antagonist 2 has high bioavailability in vivo.TLR7/8/9 antagonist 2 can be used for the research of auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.
- SMILESCN1N=CC2=C(C=C(C)N=C21)N(CC3)CCC3C4=NC=C(N5CCNCC5)C=C4C
- Storage InstructionSee Manual
- UNSPSC12352200