TM2D1 antibody

GeneTex

TM2D1 antibody

9

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

TM2D1

TM2 domain containing 1

amyloid-beta-binding protein; BBP; Beta-amyloid peptide binding protein; beta-amyloid-binding protein; hBBP; TM2 domain-containing protein 1

Rabbit

IgG

TM2 domain-containing protein 1

The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimers disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203