TMEM59 Antibody, HRP conjugated
CSB-PA023860LB01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetTMEM59
Overview
- SupplierCusabio
- Product NameTMEM59 Antibody, HRP conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateHRP
- Gene ID9528
- Target nameTMEM59
- Target descriptiontransmembrane protein 59
- Target synonymsC1orf8; DCF1; dendritic cell factor 1; HSPC001; liver membrane-bound protein; PRO195; transmembrane protein 59; UNQ169
- HostRabbit
- IsotypeIgG
- Protein IDQ9BXS4
- Protein NameTransmembrane protein 59
- Scientific DescriptionActs as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy (PubMed:27273576, PubMed:23376921). Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP (PubMed:20427278). Inhibits APP transport to the cell surface and further shedding (PubMed:20427278).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203