Fig-1: Induction of TNF-alpha promoter activity by LPS in TNF-alpha RAW264.7 cells.
Fig-1: Induction of TNF-alpha promoter activity by LPS in TNF-alpha RAW264.7 cells.
TNF-alpha Luciferase Reporter-RAW264.7 Cell Line
RC1006
Product group (Cell) Culture
Overview
- SupplierBoster Bio
- Product NameTNF-alpha Luciferase Reporter-RAW264.7 Cell Line
- Delivery Days Customer9
- ApplicationsFunctional Assay
- CertificationResearch Use Only
- Scientific DescriptionThe TNF-alpha Luciferase Reporter cell line is a stably transfected RAW264.7 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the TNF-alpha promoter. Tumor necrosis factor-alpha (TNF-alpha) is one of the major proinflammatory cytokines and can induce systemic inflammation, apoptotic cell death, sepsis and cachexia. Dysregulation of TNF-alpha induction is often involved in various human diseases including inflammatory bowel disease, cancer and Alzheimers disease. The TNF-alpha induction by lipopolysaccharide (LPS), the Toll-like receptor 4 (TLR4) ligand, is shown in Figure 1.
- Storage InstructionLiquid Nitrogen
- UNSPSC12352207