TNF-alpha/TNFSF2, Cynomolgus (Biotinylated)
HY-P77543
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameTNF-alpha/TNFSF2, Cynomolgus (Biotinylated)
- Delivery Days Customer5
- CertificationResearch Use Only
- Estimated Purity98.0
- Scientific DescriptionTumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine[1]. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death[2]. TNF alpha stimulates NF-kappaB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-alpha MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse[3]. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury[4]. TNF-alpha/TNFSF2 Protein, Cynomolgus (Biotinylated) is a biotinylated recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.
- Storage Instruction-80°C
- UNSPSC12352202