Bio-Connect
The data was published in the journal Front Immunol in 2019. PMID: 31921183
The data was published in the journal Front Immunol in 2019. PMID: 31921183
The data was published in the journal Front Immunol in 2019. PMID: 31921183

TNF Receptor I antibody [HM104] (PE)

GTX16198
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
Product group Antibodies
ReactivityMouse
TargetTnfrsf1a
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    TNF Receptor I antibody [HM104] (PE)
  • Delivery Days Customer
    9
  • Antibody Specificity
    Recognizes an extracellular region of mouse TNF Receptor I (also known as TNFR1, p55)
  • Application Supplier Note
    FACS: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HM104
  • Concentration
    0.10 mg/ml
  • Conjugate
    RPE
  • Gene ID21937
  • Target name
    Tnfrsf1a
  • Target description
    tumor necrosis factor receptor superfamily, member 1a
  • Target synonyms
    CD120; CD120a; FPF; p5; p55; p55-R; p60; TN; Tnf; TNF-; TNF receptor alpha chain; TNF-a; TNFal; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; Tnfr1; TNF-R1; Tnfr-2; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; tumor necrosis factor receptor 1; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor type I
  • Host
    Rat
  • Isotype
    IgG2a
  • Protein IDP25118
  • Protein Name
    Tumor necrosis factor receptor superfamily member 1A
  • Scientific Description
    This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mice lacking a functional copy of this gene exhibit impaired immune function. [provided by RefSeq, Sep 2016]
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • TNF-alpha Directly Enhances Osteocyte RANKL Expression and Promotes Osteoclast Formation. Marahleh A et al., 2019, Front Immunol
    Read more