
The data was published in the journal Front Immunol in 2019. PMID: 31921183
TNF Receptor I antibody [HM104] (PE)
GTX16198
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
Product group Antibodies
ReactivityMouse
TargetTnfrsf1a
Overview
- SupplierGeneTex
- Product NameTNF Receptor I antibody [HM104] (PE)
- Delivery Days Customer9
- Antibody SpecificityRecognizes an extracellular region of mouse TNF Receptor I (also known as TNFR1, p55)
- Application Supplier NoteFACS: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHM104
- Concentration0.10 mg/ml
- ConjugateRPE
- Gene ID21937
- Target nameTnfrsf1a
- Target descriptiontumor necrosis factor receptor superfamily, member 1a
- Target synonymsCD120; CD120a; FPF; p5; p55; p55-R; p60; TN; Tnf; TNF-; TNF receptor alpha chain; TNF-a; TNFal; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; Tnfr1; TNF-R1; Tnfr-2; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; tumor necrosis factor receptor 1; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor type I
- HostRat
- IsotypeIgG2a
- Protein IDP25118
- Protein NameTumor necrosis factor receptor superfamily member 1A
- Scientific DescriptionThis gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mice lacking a functional copy of this gene exhibit impaired immune function. [provided by RefSeq, Sep 2016]
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- TNF-alpha Directly Enhances Osteocyte RANKL Expression and Promotes Osteoclast Formation. Marahleh A et al., 2019, Front ImmunolRead more