TNFRSF11B Antibody, HRP conjugated

Cusabio

TNFRSF11B Antibody, HRP conjugated

20

ELISA

Research Use Only

Polyclonal

HRP

Rabbit

IgG

Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.

Human

-20°C or -80°C

12352203