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TNIK Antibody, FITC conjugated

CSB-PA023998LC01HU
Cusabio
ReactivityHuman
Product group Antibodies
TargetTNIK
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Overview

  • Supplier
    Cusabio
  • Product Name
    TNIK Antibody, FITC conjugated
  • Delivery Days Customer
    20
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    FITC
  • Gene ID23043
  • Target name
    TNIK
  • Target description
    TRAF2 and NCK interacting kinase
  • Target synonyms
    MRT54; TRAF2 and NCK-interacting protein kinase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UKE5
  • Protein Name
    TRAF2 and NCK-interacting protein kinase
  • Scientific Description
    Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203