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Western Blot Positive WB detected in: Jurkat whole cell lysate All lanes: TNKS antibody at 4.8microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 143, 68 kDa Observed band size: 143, 68 kDa
Western Blot Positive WB detected in: Jurkat whole cell lysate All lanes: TNKS antibody at 4.8microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 143, 68 kDa Observed band size: 143, 68 kDa
Western Blot Positive WB detected in: Jurkat whole cell lysate All lanes: TNKS antibody at 4.8microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 143, 68 kDa Observed band size: 143, 68 kDa

TNKS Antibody

CSB-PA024004LA01HU
Cusabio
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTNKS
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Overview

  • Supplier
    Cusabio
  • Product Name
    TNKS Antibody
  • Delivery Days Customer
    20
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID8658
  • Target name
    TNKS
  • Target description
    tankyrase
  • Target synonyms
    ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; PARP5A; PARP-5a; PARPL; pART5; poly [ADP-ribose] polymerase 5A; poly [ADP-ribose] polymerase tankyrase-1; protein poly-ADP-ribosyltransferase tankyrase-1; TANK1; tankyrase I; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; tankyrase-1; TIN1; TINF1; TNKS1; TNKS-1; TRF1-interacting ankyrin-related ADP-ribose polymerase 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO95271
  • Protein Name
    Tankyrase-1
  • Scientific Description
    Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length. Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. May be involved in spindle pole assembly through PARsylation of NUMA1. Stimulates 26S proteasome activity.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203