Top/HDAC-IN-1
T63509
Overview
- SupplierTargetMol Chemicals
- Product NameTop/HDAC-IN-1
- Delivery Days Customer114
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameTop/HDAC-IN-1
- Molecular FormulaC29H27N5O4
- Molecular Weight509.56
- Scientific DescriptionTop/HDAC-IN-1 is a dual topoisomerase (Top)/HDAC inhibitor that acts on HDAC1 (IC50: 18 nM), HDAC2 (IC50: 230 nM), HDAC3 (IC50: 790 nM), HDAC6 (IC50: 87 nM) and HDAC8 (IC50: 5250 nM). Top/HDAC-IN-1 exhibited potent antitumor effects on HCT116 cells (IC50: 180 nM), blocked the cell cycle of HCT116 cells in G2 phase, and effectively induced apoptosis.
- Shelf life instruction3 years
- Storage Instruction-20°C
- UNSPSC51202000