TOPK-p38/JNK-IN-1 [2745108-35-2]

TargetMol Chemicals

TOPK-p38/JNK-IN-1 [2745108-35-2]

72

Chemical

Research Use Only

TOPK-p38/JNK-IN-1

C17H15F3N2O4

368.31

TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, exhibiting an IC50 of 2.14 microM for NO production inhibition. It demonstrates anti-inflammatory properties by inhibiting downstream protein phosphorylation and preventing TOPK degradation [1].

3 years

N(C(NC1=CC(C(F)(F)F)=CC=C1)=O)C2=C(OC)C=C(O)C(C(C)=O)=C2

-20°C

51202000