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Topoisomerase II alpha (Proliferation & Drug-Resistance Marker) (TOP2A/1361), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC401361
Biotium
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetTOP2A
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Overview

  • Supplier
    Biotium
  • Product Name
    Topoisomerase II alpha (Proliferation & Drug-Resistance Marker) (TOP2A/1361), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    TOP2A/1361
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID7153
  • Target name
    TOP2A
  • Target description
    DNA topoisomerase II alpha
  • Target synonyms
    DNA gyrase; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase 2-alpha; DNA topoisomerase II, 170 kD; DNA topoisomerase II, alpha isozyme; TOP2; TOP2alpha; TOPIIA; topoisomerase (DNA) II alpha 170kDa; TP2A
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP11388
  • Protein Name
    DNA topoisomerase 2-alpha
  • Scientific Description
    This antibody recognizes a 170 kDa protein, which is identified as topoisomerase IIalpha. It shows no cross-reaction with topoisomerase IIbeta or topoisomerase I. Topo IIalpha plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo IIalpha is also implicated in drug resistance of tumor cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203