Topoisomerase IIalpha-IN-6

MedChem Express

Topoisomerase IIalpha-IN-6

10

Research Use Only

C23H24Cl3N5O4

540.83

Topoisomerase IIalpha-IN-6 (Compound 47d) is an inhibitor of DNA topoisomerase IIalpha/beta. Topoisomerase IIalpha-IN-6 inhibits human topoisomerase IIalpha and human topoisomerase IIbeta with IC50 values of 0.67 microM and 0.55 microM, respectively. Topoisomerase IIalpha-IN-6 has stable metabolism[1].

CC1=C(C(Cl)=C(N1)C(NC2=CC=C(C=C2OCC3=CC=C(C=C3)C(NCCN)=O)C(N)=O)=O)Cl.Cl

12131703