Topoisomerase IIalpha-IN-7

MedChem Express

Topoisomerase IIalpha-IN-7

10

Research Use Only

C25H27Cl3N4O3

537.87

Topoisomerase IIalpha-IN-7 is an DNA topoisomerase IIalpha inhibitor with an IC50 value of 7.7 microM. Topoisomerase IIalpha-IN-7 has broad-spectrum cytotoxicity to leukemia, lung, colon, melanoma, ovarian, kidney, prostate and breast cancer cells. Topoisomerase IIalpha-IN-7 has metabolic stability[1].

O=C(NC1=C(OCC2=CC(C(NC3CCCNC3)=O)=CC=C2)C=CC=C1)C4=C(Cl)C(Cl)=C(C)N4.Cl

12131703