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ProductsBack/Tos-PEG4-t-butyl ester [217817-01-1]
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Tos-PEG4-t-butyl ester [217817-01-1]

Research Use Only
T17133
TargetMol Chemicals
CAS Number217817-01-1
Product group Chemicals
Molecular Weight432.53
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Tos-PEG4-t-butyl ester
  • Delivery Days Customer
    14
  • CAS Number
    217817-01-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Tos-PEG4-t-butyl ester
  • Molecular Formula
    C20H32O8S
  • Molecular Weight
    432.53
  • Scientific Description
    Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker characterized by its PEG composition, crucial in synthesizing various PROTACs, including BI-3663, a selective PTK2/FAK PROTAC. Using cereblon ligands, it targets E3 ligases to degrade PTK2, exhibiting potent inhibitory activity with an IC50 of 18 nM[1].
  • Shelf life instruction
    3 years
  • SMILES
    S(OCCOCCOCCOCCC(OC(C)(C)C)=O)(=O)(=O)C1=CC=C(C)C=C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200