TP-472

MedChem Express

TP-472 [2079895-62-6]

10

2079895-62-6

99.52

C20H19N3O2

333.38

TP-472 is a selective BRD9/7 inhibitor, with K d s of 33 nM and 340 nM for BRD9 and BRD7, respectively. TP-472 exhibits >30-fold selectivity for BRD9 over other bromodomain family members except BRD7 [1] [2] . TP-472 induces apoptosis of melanoma cells [3] .

O=C(C)C1=CC(C2=C(C)C=CC(C(NC3CC3)=O)=C2)=C4N=CC=CN41

-20°C,2°C to 8°C

12352200