TP0427736 HCl [864374-00-5]
S8700
CAS Number864374-00-5
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameTP0427736 HCl [864374-00-5]
- Delivery Days Customer9
- CAS Number864374-00-5
- CertificationResearch Use Only
- Scientific DescriptionTP0427736 is a potent inhibitor of ALK5 kinase activity with an IC50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50 = 836 nM for ALK3). It also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-bèta1 with an IC50 value of 8.68 nM.
- UNSPSC12352200