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Western Blot Positive WB detected in: PC3 whole cell lysate All lanes: TP63 antibody at 2.1microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 66, 63, 52, 56, 45, 58, 47, 68, 57, 77 KDa Observed band size: 77 KDa
Western Blot Positive WB detected in: PC3 whole cell lysate All lanes: TP63 antibody at 2.1microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 66, 63, 52, 56, 45, 58, 47, 68, 57, 77 KDa Observed band size: 77 KDa
Western Blot Positive WB detected in: PC3 whole cell lysate All lanes: TP63 antibody at 2.1microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 66, 63, 52, 56, 45, 58, 47, 68, 57, 77 KDa Observed band size: 77 KDa

TP63 Recombinant Monoclonal Antibody

CSB-RA887971A0HU
Cusabio
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTP63
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Overview

  • Supplier
    Cusabio
  • Product Name
    TP63 Recombinant Monoclonal Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    4B3
  • Conjugate
    Unconjugated
  • Gene ID8626
  • Target name
    TP63
  • Target description
    tumor protein p63
  • Target synonyms
    AIS; amplified in squamous cell carcinoma; B(p51A); B(p51B); chronic ulcerative stomatitis protein; EEC3; keratinocyte transcription factor KET; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4; TP53CP; TP53L; TP73L; transformation-related protein 63; tumor protein 63; tumor protein p53-competing protein
  • Isotype
    IgG
  • Protein IDQ9H3D4
  • Protein Name
    Tumor protein 63
  • Scientific Description
    Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203