Western blot analysis of extracts from HuvEc cells (Lane 2), using TPH2 (Ab-19) antiobdy. The lane on the left is treated with systhesized peptide.
Western blot analysis of extracts from HuvEc cells (Lane 2), using TPH2 (Ab-19) antiobdy. The lane on the left is treated with systhesized peptide.
TPH2 (Ab-19) Antibody
CSB-PA272667
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetTPH2
Overview
- SupplierCusabio
- Product NameTPH2 (Ab-19) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID121278
- Target nameTPH2
- Target descriptiontryptophan hydroxylase 2
- Target synonymsADHD7; neuronal tryptophan hydroxylase; NTPH; tryptophan 5-hydroxylase 2; tryptophan 5-monooxygenase 2
- HostRabbit
- IsotypeIgG
- Protein IDQ8IWU9
- Protein NameTryptophan 5-hydroxylase 2
- Scientific DescriptionThis gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. Bader M., Science 299:76-76(2003). Gibbs R.A., Nature 440:346-351(2006). Pandey A., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203