Tpl2 Kinase Inhibitor 1

MedChem Express

Tpl2 Kinase Inhibitor 1 [871307-18-5]

10

871307-18-5

Research Use Only

99.42

C21H14ClFN6

404.83

Tpl2 Kinase Inhibitor 1 is a 3-pyridylmethylamino analog, and is a selective Tpl2 inhibitor (IC50=50 nM). Tpl2 consists of COT kinase and MAP3K8. Tpl2 Kinase Inhibitor 1 plays an important role in the regulation of the inflammatory response and the progression of some cancers[1][2].

N#CC1=C(NC2=CC=C(F)C(Cl)=C2)C3=CC(NCC4=CC=CN=C4)=NC=C3N=C1

-20°C

12352200