TPM3 Polyclonal Antibody

Reddot Biotech

TPM3 Polyclonal Antibody

5

1 mg/ml

TPM3

tropomyosin 3

alpha-tropomyosin, slow skeletal; CAPM1; CFTD; cytoskeletal tropomyosin TM30; epididymis luminal protein 189; epididymis secretory sperm binding protein Li 82p; heat-stable cytoskeletal protein 30 kDa; HEL-189; HEL-S-82p; hscp30; NEM1; OK/SW-cl.5; TM3; TM30; TM30nm; TM5; TM-5; TPM3nu; TPMsk3; TRK; tropomyosin 3 nu; tropomyosin alpha-3 chain; tropomyosin gamma; tropomyosin-5

This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.

-20°C

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