TPMPA

MedChem Express

TPMPA [182485-36-5]

10

182485-36-5

Research Use Only

98.1

C6H12NO2P

161.14

TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABA C receptor ( K B = 2.1 microM), but not to interact with GABA A ( K B = 320 microM) or GABA B receptors ( EC 50 = 500 microM). TPMPA has the potential for the research of suppressing orientation selectivity in ganglion cells [1] [2] [3] .

O=P(C1=CCNCC1)(C)O

-20°C

12352200