TPN171 [1229018-87-4]

TargetMol Chemicals

TPN171 [1229018-87-4]

4

1229018-87-4

Chemical

Research Use Only

TPN171

C24H35N5O3

441.57

TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6, which has the potential for the treatment of pulmonary arterial hypertension (PAH). TPN171 was proven to exert a longer lasting effect than sildenafil in animal models, providing a foundation for a once-daily oral administration for its clinical use.

3 years

CCCOc1ccc(NC(=O)CN2CCN(C)CC2)cc1-c1nc(CC)c(CC)c(=O)[nH]1

-20°C

12352200