Bio-Connect
TPO (Thyroid Peroxidase) (Thyroid Marker)(TPO/3813R), CF405S conjugate, 0.1mg/mL [26628-22-8]

TPO (Thyroid Peroxidase) (Thyroid Marker)(TPO/3813R), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC043813
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTPO
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biotium
  • Product Name
    TPO (Thyroid Peroxidase) (Thyroid Marker)(TPO/3813R), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    TPO/3813R
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID7173
  • Target name
    TPO
  • Target description
    thyroid peroxidase
  • Target synonyms
    MSA; TDH2A; thyroid microsomal antigen; thyroid peroxidase; thyroperoxidase; TPX
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP07202
  • Protein Name
    Thyroid peroxidase
  • Scientific Description
    Thyroperoxidase (TPO) is a 933-amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203