TPT1 Polyclonal Antibody

Reddot Biotech

TPT1 Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.8 mg/ml

Unconjugated

TPT1

tumor protein, translationally-controlled 1

fortilin; histamine-releasing factor; HRF; p02; p23; TCTP; translationally-controlled tumor protein

Rabbit

IgG

This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5-TOP) in its 5 untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Human, Mouse, Rat

-20°C

12352203