TRADD Polyclonal Antibody
RD80602A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetTRADD
Overview
- SupplierReddot Biotech
- Product NameTRADD Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8717
- Target nameTRADD
- Target descriptionTNFRSF1A associated via death domain
- Target synonymsHs.89862; TNFR1-associated death domain protein; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor-1-associated protein
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203