TRAIL/TNFSF10, Mouse (His,Solution)

MedChem Express

TRAIL/TNFSF10, Mouse (His,Solution)

5

Research Use Only

95.50

Tumor necrosis factor ligand superfamily member 10

TRAIL Protein (TNFSF10), a member of the TNF superfamily, is a type II transmembrane protein. TRAIL Protein mainly interacts with TRAIL-R1 and TRAIL-R2, and induces apoptosis in tumor or infected cells. TRAIL Protein also binds with DR4, DR5, and OPG. TRAIL Protein can recruit FADD and further recruit and activates caspase-8 after binding to DR4 or DR5. Besides, TRAIL may also trigger nonapoptotic signaling through activating pro-inflammatory pathways[1][2]. TRAIL protein is mainly expressed on surface of immune cells, such as cytotoxic T cells and natural killer (NK) cell[1]. TRAIL/TNFSF10 Protein, Mouse (His) is a recombinant mouse TRAIL (P118-N291) with N-terminal His tag, which is expressed in E.coli.

-80°C

12352202