trans-J-113863

MedChem Express

trans-J-113863

14

Research Use Only

C30H37Cl2IN2O2

655.44

trans-J-113863 is a potent chemokine CCR1 and CCR3 receptor antagonist, and inhibits MIP-1alpha-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants with IC 50 s of 9.57 and 93.8 nM,respectively [1] [2] .

CC[N@+]1(C/C2=C/CCCCCC2)CC[C@H](NC(C3C4=C(OC5=C3C=C(Cl)C=C5)C=CC(Cl)=C4)=O)CC1.[I-]

12352200