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ProductsBack/Transferrin Receptor Antibody / TFRC / CD71 / Extracellular domain

Transferrin Receptor Antibody / TFRC / CD71 / Extracellular domain

Research Use Only
ORB639953
Biorbyt
ApplicationsImmunoHistoChemistry
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Product group Antibodies
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Transferrin Receptor Antibody / TFRC / CD71 / Extracellular domain
  • Delivery Days Customer
    16
  • Applications
    ImmunoHistoChemistry
  • Applications Supplier
    Immunohistochemistry (FFPE): 1-2ug/ml IHC-P
  • Certification
    Research Use Only
  • Clone ID
    TFRC/2898R
  • Isotype
    IgG
  • Scientific Description
    It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
  • UNSPSC
    12352203