Transferrin Receptor Antibody / TFRC / CD71

Biorbyt

Transferrin Receptor Antibody / TFRC / CD71

16

Optimal dilution of the CD71 antibody should be determined by the researcher.

ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

ELISA: 2-4ug/ml (order BSA/azide-free format),Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT Western blot: 0.5-1ug/ml ELISA, IHC-P

Research Use Only

Monoclonal

TFRC/1817

Unconjugated

TFRC

transferrin receptor

CD71; IMD46; p90; T9; TFR; TFR1; TR; transferrin receptor protein 1; TRFR

Mouse

IgG2b

Transferrin receptor protein 1

It recognizes a ~85-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Human

-20°C,2°C to 8°C

12352203