Triciferol [957214-00-5]

TargetMol Chemicals

Triciferol [957214-00-5]

114

957214-00-5

Chemical

Research Use Only

Triciferol

C26H39NO4

429.59

Triciferol acts as a multiple ligand with combined VDR agonist and HDAC antagonist activities. Triciferol binds directly to the VDR ( IC 50 =87 nM), and functions as an agonist with 1,25D-like potency on several 1,25D target genes. Triciferol induces marked tubulin hyperacetylation, and augments histone acetylation. Triciferol also exhibits efficacious antiproliferative and cytotoxic activities in cancer cell models in vitro [1].

3 years

[H][C@@]12CC[C@H]([C@H](C)\C=C(/C)\C=C\C(=O)NO)[C@@]1(C)CCC\C2=C/C=C1C[C@@H](O)C[C@H](O)C1

-20°C

12352200