Triciribine phosphate

MedChem Express

Triciribine phosphate [61966-08-3]

14

61966-08-3

Research Use Only

99.0

C13H17N6O7P

400.28

Triciribine phosphate (TCN-P) inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate also inhibits IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity [1] .

NC1=NN(C)C2=C3C1=CN([C@@H]4O[C@@H]([C@H]([C@H]4O)O)COP(O)(O)=O)C3=NC=N2

-20°C

12352200