Trimipramine (maleate) (Standard) [521-78-8]

MedChem Express

Trimipramine (maleate) (Standard) [521-78-8]

9

521-78-8

Research Use Only

C24H30N2O4

410.51

Trimipramine (maleate) (Standard) is the analytical standard of Trimipramine (maleate). This product is intended for research and analytical applications. Trimipramine maleate is a 5-HT receptor antagonist, with pKi binding values of 6.39, 8.10, 4.66 for 5-HT1C, 5-HT2 and 5-HT1A, respectively[1]. Trimipramine maleate is also a potent and selective inhibitor targeting human noradrenaline (hNAT), serotonin (hSERT) and organic cation transporters (hOCT1, hOCT2) with IC50 values of 4.99 microM, 2.11 microM, 3.72 microM, 8.00 microM, respectively[2]. Trimipramine maleate has vascular activity and anxiolytic efficacy[3].

CC(CN(C)C)CN1C2=C(C=CC=C2)CCC3=C1C=CC=C3.O=C(O)/C=C\C(O)=O

41116135