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ProductsBack/Tripolin A [1148118-92-6]
Chemical Structure
Chemical Structure
Chemical Structure

Tripolin A [1148118-92-6]

Research Use Only
AG-CR1-3520
AdipoGen Life Sciences
CAS Number1148118-92-6
DownloadMSDS
Product group Chemicals
Estimated Purity>98%
Molecular Weight253.3
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Tripolin A [1148118-92-6]
  • Delivery Days Customer
    10
  • CAS Number
    1148118-92-6
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C15H11NO3
  • Molecular Weight
    253.3
  • Scientific Description
    Chemical. CAS: 1148118-92-6. Formula: C15H11NO3. MW: 253.3. Specific non-ATP competitive Aurora A kinase inhibitor. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase. - Specific non-ATP competitive Aurora A kinase inhibitor [1]. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase [1].
  • SMILES
    OC1=CC=C(O)C(\C=C2/C(=O)NC3=C2C=CC=C3)=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Tripolin A, a novel small-molecule inhibitor of aurora A kinase, reveals new regulation of HURP's distribution on microtubules: I.A. Kesisova, et al.; PLoS One 8, e58485 (2013)