TrkA inhibitor compound 23 (TrkA-IN-23)

Biorbyt

TrkA inhibitor compound 23 (TrkA-IN-23) [1821484-84-7]

16

1821484-84-7

Research Use Only

C26H23Cl2N5O3

524.402

TrkA inhibitor compound 23 is an allosteric, potent, Subtype Selective and Peripherally Restricted TrkA Kinase Inhibitor, with IC50 of 10 nM, 180-fold selective over TrkB and 70-fold selective over TrkC in cell based assays.

C1=CC=CC(C2=C(Cl)C=C(Cl)C(C(=O)NC3N(C4=CC=CC=C4)N=C(C(=O)NCC(C)(C)O)C=3)=C2)=N1

12352200