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ProductsBack/TrkB antibody

TrkB antibody

GTX133722
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityMouse, Rat
TargetNtrk2
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Overview

  • Supplier
    GeneTex
  • Product Name
    TrkB antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.24 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID18212
  • Target name
    Ntrk2
  • Target description
    neurotrophic tyrosine kinase, receptor, type 2
  • Target synonyms
    BDNF/NT-3 growth factors receptor; GP145-TrkB/GP95-TrkB; neurotrophic tyrosine receptor kinase type 2; Tkr; Tkrb; trk; trkB; trk-B; trkB tyrosine kinase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP15209
  • Protein Name
    BDNF/NT-3 growth factors receptor
  • Scientific Description
    Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Environmental Enrichment Induces Meningeal Niche Remodeling through TrkB-Mediated Signaling. Zorzin S et al., 2021 Oct 1, Int J Mol Sci
    Read more
  • Ultrasound Stimulation Suppresses LPS-Induced Proinflammatory Responses by Regulating NF-kappaB and CREB Activation in Microglial Cells. Chang JW et al., 2020 Jun 30, Cereb Cortex
    Read more
  • Postnatal Lipopolysaccharide Exposure Impairs Adult Neurogenesis and Causes Depression-like Behaviors Through Astrocytes Activation Triggering GABAA Receptor Downregulation. Liang M et al., 2019 Dec 1, Neuroscience
    Read more